Bringing Network Pharmacology to OpenCog Hyperon
Antecedens e.U. proposes a project aimed at developing a tool to integrate well-curated knowledge graphs from the field of network pharmacology into OpenCog Hyperon. This project serves multiple purposes, including supporting OpenCog Hyperon's language MeTTa and Probabilistic Logic Networks (PLN) development, contributing to SingularityNET's web3 initiative, and sharing insights with the Rejuve team in the biomedicine domain. The tool's goal is to enable the derivation of novel pharmacological relationships and hypotheses through OpenCog Hyperon's advanced querying and reasoning capabilities.
The project requests $40,000 in funding, aligning with RFP4's objective of integrating knowledge graphs with Large Language Models (LLMs). It aims to develop a Python package to retrieve, convert, and import up-to-date knowledge graphs from biomedicine, focusing on pharmacology, into OpenCog Hyperon. The project identifies several high-quality knowledge graph projects in biomedicine and plans to bring them into OpenCog Hyperon through this Python package.
The project outlines milestones, including a literature review, design discussions with MeTTa and PLN teams, implementation phases for integrating knowledge graphs, documentation, and finalization. Potential risks are identified, such as changes in MeTTa's API stability, unforeseen issues with knowledge graphs, and potential redundancies with Rejuve. Mitigations are proposed for each risk.
In summary, Antecedens e.U. aims to enhance OpenCog Hyperon's capabilities by integrating knowledge graphs from network pharmacology, contributing to SingularityNET's web3 initiative, and fostering collaboration in the biomedicine domain. The project requests $40,000 in funding to achieve these goals.